intercellular cell adhesion molecule 1 icam 1 (Santa Cruz Biotechnology)
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Santa Cruz Biotechnology
intercellular cell adhesion molecule 1 icam 1
Intercellular Cell Adhesion Molecule 1 Icam 1, supplied by Santa Cruz Biotechnology, used in various techniques. Bioz Stars score: 96/100, based on 4723 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/anti+intercellular+cell+adhesion+molecule+1/ICAM-1+Antibody/pm36293441-235-20-37
Average 96 stars, based on 4723 article reviews
Intercellular Cell Adhesion Molecule 1 Icam 1, supplied by Santa Cruz Biotechnology, used in various techniques. Bioz Stars score: 96/100, based on 4723 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/anti+intercellular+cell+adhesion+molecule+1/ICAM-1+Antibody/pm36293441-235-20-37
Average 96 stars, based on 4723 article reviews
intercellular cell adhesion molecule 1 icam 1 - by Bioz Stars,
2026-08
96/100 stars
Images
1) Product Images from "Downregulation of P300/CBP-Associated Factor Protects from Vascular Aging via Nrf2 Signal Pathway Activation."
Article Title: Downregulation of P300/CBP-Associated Factor Protects from Vascular Aging via Nrf2 Signal Pathway Activation.
Journal: International journal of molecular sciences
doi: 10.3390/ijms232012574
Figure Legend Snippet: Figure 1. PCAF is highly expressed in coronary arteries of elderly patients and human atherosclerotic vessels. (A) All specimens were obtained from the proximal right coronary artery of the patient, and the expression of PCAF in human coronary arteries was detected by immunochemistry. The representative slides are shown; the scale bar is 1 mm, 2×. (B) The relationship between patient age and PCAF expression in human coronary arteries (n = 44). (C,D) The coronary intima produced “atherosclerotic plaque” as the criterion for judging atherosclerosis (AS). Western blot detects PCAF expression and aging-related protein (p53, p21, p16, ICAM-1 and VCAM-1) levels in human coronary arteries (n = 3). (E,F) Nrf2 signal pathway related protein level was detected by western blot (n = 3). ** p < 0.01 vs. the control group.
Techniques Used: Expressing, Produced, Western Blot, Control
Figure Legend Snippet: Figure 2. Downregulation of PCAF inhibits AngII-induced senescence of ECs. (A,B) Western blot to determine the expression of PCAF in each group (n = 6). (C,D) β-galactosidase staining to detect senescence of ECs; Senescent VSMCs were marked in blue, the scale bar is 100 µm, 400× (n = 5). (E,F) p53, p21, p16, ICAM-1 and VCAM-1 protein expression (n = 6). (G) Detection of PCAF (green) and p21 (red) levels by immunofluorescence double staining; the scale bar is 100 µm, 400× (n = 3). ** p < 0.01 vs. the control group; # p < 0.05, ## p < 0.01 vs. the AngII induction with Ad-GFP group (AngII + Ad-GFP group).
Techniques Used: Western Blot, Expressing, Staining, Double Staining, Control
Figure Legend Snippet: Figure 3. The PCAF inhibitor garcinol significantly attenuates the AngII-induced vascular ag- ing phenotype in mice. (A) H&E staining to observe the vascular structure—the scale bar is 100 µm, 100× (n = 3); immunofluorescence staining to detect the expression of PCAF (green) and p53 (red)—the scale bar is 100 µm, 200× (n = 3). (B) Detection of p16 (red) and p21 (green) expression in mice thoracic aorta by double immunofluorescence staining; the scale bar is 100 µm, 400× (n = 3). (C,D) Western blot detects the expression of PCAF, aging-related proteins (p53, p21, p16, VCAM-1 and ICAM-1) and Nrf2 signaling pathway proteins in mice thoracic aorta (n = 6). ** p < 0.01 vs. the Sham group; # p < 0.05, ## p < 0.01 vs. AngII group.
Techniques Used: Staining, Expressing, Western Blot